In 1975 the Ohio Department of Natural Resources (ODNR) completed a project review of the proposed Old Woman Creek natural estuary. The plan was to buy over 500 acres of land from property owners to establish the first national estuarine sanctuary on the Great Lakes.
Funded by ODNR and matching federal funds from the Office of Coastal Zone Management of the Department of Commerce, the Old Woman Creek National Estuarine Research Reserve estuary was dedicated in 1980 as a part of the ODNR system of state nature preserves.